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Covid vaccines effectiveness and boosters

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  • Pfizer’s COVID-19 Vaccine Goes Into Liver Cells and Is Converted to DNA: Study

    The messenger RNA (mRNA) from Pfizer’s COVID-19 vaccine is able to enter human liver cells and is converted into DNA, according to Swedish researchers at Lund University.

    The researchers found that when the mRNA vaccine enters the human liver cells, it triggers the cell’s DNA, which is inside the nucleus, to increase the production of the LINE-1 gene expression to make mRNA.

    The mRNA then leaves the nucleus and enters the cell’s cytoplasm, where it translates into LINE-1 protein. A segment of the protein called the open reading frame-1, or ORF-1, then goes back into the nucleus, where it attaches to the vaccine’s mRNA and reverse transcribes into spike DNA.

    Reverse transcription is when DNA is made from RNA, whereas the normal transcription process involves a portion of the DNA serving as a template to make an mRNA molecule inside the nucleus.

    “In this study we present evidence that COVID-19 mRNA vaccine BNT162b2 is able to enter the human liver cell line Huh7 in vitro,” the researchers wrote in the study, published in Current Issues of Molecular Biology. “BNT162b2 mRNA is reverse transcribed intracellularly into DNA as fast as 6 [hours] after BNT162b2 exposure.”

    BNT162b2 is another name for the Pfizer-BioNTech COVID-19 vaccine that is marketed under the brand name Comirnaty.

    The whole process occurred rapidly within six hours. The vaccine’s mRNA converting into DNA and being found inside the cell’s nucleus is something that the Centers for Disease Control and Prevention (CDC) said would not happen.

    “The genetic material delivered by mRNA vaccines never enters the nucleus of your cells,” the CDC said on its web page titled “Myths and Facts about COVID-19 Vaccines.”

    This is the first time that researchers have shown in vitro or inside a petri dish how an mRNA vaccine is converted into DNA on a human liver cell line, and is what health experts and fact-checkers said for over a year couldn’t occur.

    The CDC says that the “COVID-19 vaccines do not change or interact with your DNA in any way,” claiming that all of the ingredients in both mRNA and viral vector COVID-19 vaccines (administered in the United States) are discarded from the body once antibodies are produced. These vaccines deliver genetic material that instructs cells to begin making spike proteins found on the surface of SARS-CoV-2 that causes COVID-19 to produce an immune response.

    Pfizer didn’t comment on the findings of the Swedish study and said only that its mRNA vaccine does not alter the human genome.

    “Our COVID-19 vaccine does not alter the DNA sequence of a human cell,” a Pfizer spokesperson told The Epoch Times in an email. “It only presents the body with the instructions to build immunity.”

    More than 215 million or 64.9 percent of Americans are fully vaccinated as of Feb. 28, with 94 million having received a booster dose.
    Study

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    • This is too far outside my field to follow, but I asked a friend who's a scientist with a relevant background.

      He sees no cause for concern with regard to this because:
      - If the vaccine does this, actually catching the virus would almost certainly do the same thing but more so.
      - The cells they are testing it on are not normal human liver cells and have been altered.
      - Specifically the mechanism, L1 LINE, is inhibited in normal human cells by multiple mechanisms, so he would not expect this behavior in normal human cells.

      I would add that if you're receiving the vaccine in your liver rather than your arm muscle, you're doing it very wrong.
      "I hate him passionately", he's "a demonic force" - Tucker Carlson, in private, on Donald Trump
      "Every line of serious work that I have written since 1936 has been written, directly or indirectly, against totalitarianism and for democratic socialism" - George Orwell
      "[Capitalism] as it exists today is, in my opinion, the real source of evils. I am convinced there is only one way to eliminate these grave evils, namely through the establishment of a socialist economy" - Albert Einstein

      Comment


      • Originally posted by Starlight View Post
        Those graphs show in stark terms what a difference vaccines make.
        They also show that while omicron is not as bad as previous variants, it's still nasty.

        Jorge: Functional Complex Information is INFORMATION that is complex and functional.

        MM: First of all, the Bible is a fixed document.
        MM on covid-19: We're talking about an illness with a better than 99.9% rate of survival.

        seer: I believe that so called 'compassion' [for starving Palestinian kids] maybe a cover for anti Semitism, ...

        Comment


        • "The vaccine’s mRNA converting into DNA and being found inside the cell’s nucleus is something that the Centers for Disease Control and Prevention (CDC) said would not happen."


          The CDC has been lying to us about quite a lot of things for at least the past two years.
          Last edited by Mountain Man; 03-04-2022, 05:41 AM.
          Some may call me foolish, and some may call me odd
          But I'd rather be a fool in the eyes of man
          Than a fool in the eyes of God


          From "Fools Gold" by Petra

          Comment


          • Originally posted by Starlight View Post
            This is too far outside my field to follow, but I asked a friend who's a scientist with a relevant background.

            He sees no cause for concern with regard to this because:
            - If the vaccine does this, actually catching the virus would almost certainly do the same thing but more so.
            - The cells they are testing it on are not normal human liver cells and have been altered.

            - Specifically the mechanism, L1 LINE, is inhibited in normal human cells by multiple mechanisms, so he would not expect this behavior in normal human cells.

            I would add that if you're receiving the vaccine in your liver rather than your arm muscle, you're doing it very wrong.
            From the study he linked:

            "A recent study showed that SARS-CoV-2 RNAs can be reverse-transcribed and integrated into the genome of human cells [25]. This gives rise to the question of if this may also occur with BNT162b2, which encodes partial SARS-CoV-2 RNA"

            "The cell model that we used in this study is a carcinoma cell line, with active DNA replication which differs from non-dividing somatic cells. It has also been shown that Huh7 cells display significant different gene and protein expression including upregulated proteins involved in RNA metabolism"

            Also it was done in vitro, (in test tubes, not a live animal)

            Comment


            • Pfizer announces a fourth booster and admits that their so-called "vaccine" does a poor job of preventing infection and doesn't last very long.

              https://townhall.com/tipsheet/rebecc...covid-n2604505
              Some may call me foolish, and some may call me odd
              But I'd rather be a fool in the eyes of man
              Than a fool in the eyes of God


              From "Fools Gold" by Petra

              Comment


              • A covid surge in Western Europe has U.S. bracing for another wave while yet another new variant has been discovered

                I'm always still in trouble again

                "You're by far the worst poster on TWeb" and "TWeb's biggest liar" --starlight (the guy who says Stalin was a right-winger)
                "Overall I would rate the withdrawal from Afghanistan as by far the best thing Biden's done" --Starlight
                "Of course, human life begins at fertilization that’s not the argument." --Tassman

                Comment


                • When they reach Omega, that's when the vampires start coming out. Just ask Charlton Heston.

                  Comment


                  • Originally posted by Mountain Man View Post
                    Pfizer announces a fourth booster and admits that their so-called "vaccine" does a poor job of preventing infection and doesn't last very long.

                    https://townhall.com/tipsheet/rebecc...covid-n2604505
                    Half truths generally are considered lies mm.

                    This is what he said:

                    Right now, the way that we have seen, it is necessary, a fourth booster right now. The protection that you are getting from the third, it is good enough, actually quite good for hospitalizations and deaths. It's not that good against infections, but doesn't last very long," Dr. Bourla said when asked by Brennan about the necessity of a fourth shot, which would be a second booster. " But we are just submitting those data to the FDA and then we will see what the experts also will say outside Pfizer," he continued to note.
                    Given that most people care more about going into a hospital for a month or dying than they do getting a sniffly nose, the vaccine most certainly does the most important thing we need it to do - it significantly reduces hospitalization and death.
                    My brethren, do not hold your faith in our glorious Lord Jesus Christ with an attitude of personal favoritism. James 2:1

                    If anyone thinks himself to be religious, and yet does not  bridle his tongue but deceives his own heart, this man’s religion is worthless James 1:26

                    This you know, my beloved brethren. But everyone must be quick to hear, slow to speak and slow to anger; James 1:19

                    Comment


                    • All the former does is show what happens when you cave to complaints about covid restrictions, and the latter is the sad reality of how this story is going to continue for quite some time, partly on account of the former.
                      My brethren, do not hold your faith in our glorious Lord Jesus Christ with an attitude of personal favoritism. James 2:1

                      If anyone thinks himself to be religious, and yet does not  bridle his tongue but deceives his own heart, this man’s religion is worthless James 1:26

                      This you know, my beloved brethren. But everyone must be quick to hear, slow to speak and slow to anger; James 1:19

                      Comment


                      • Originally posted by oxmixmudd View Post

                        All the former does is show what happens when you cave to complaints about covid restrictions, and the latter is the sad reality of how this story is going to continue for quite some time, partly on account of the former.
                        But "the science has changed"!

                        Or are you agreeing that the only thing that changed was the "POLITICAL science" as a result of polling?

                        I'm always still in trouble again

                        "You're by far the worst poster on TWeb" and "TWeb's biggest liar" --starlight (the guy who says Stalin was a right-winger)
                        "Overall I would rate the withdrawal from Afghanistan as by far the best thing Biden's done" --Starlight
                        "Of course, human life begins at fertilization that’s not the argument." --Tassman

                        Comment


                        • Originally posted by oxmixmudd View Post

                          All the former does is show what happens when you cave to complaints about covid restrictions, and the latter is the sad reality of how this story is going to continue for quite some time, partly on account of the former.
                          In china you don't complain about their "zero covid" policy restrictions because you'd disappear. And yet, in spite of that, they're having another surge. Imagine that.

                          Comment

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